That being said, if we consider the question from a philosophical and scientific standpoint, we must first understand what is meant by the “soul” and its relationship to the body.
In many spiritual and religious traditions, the soul is considered the immaterial essence or spirit of a person that gives life and consciousness to the physical body. The soul is often believed to leave the body at the moment of death and continue to exist in another realm or plane of existence.

In contrast, from a scientific perspective, consciousness and subjective experience are thought to arise from the activity of the brain and nervous system. When the brain ceases to function, consciousness and life also cease, and the body undergoes a series of physiological changes that lead to decay and decomposition.
Based on this understanding, the departure of the soul from the body would not cause physical pain, as the soul is not a physical entity that can interact with the body’s nerve endings and pain receptors. However, the process of dying itself can be accompanied by physical discomfort or pain, depending on the underlying cause of death and the individual’s health status.
For example, someone who dies from a terminal illness may experience pain and discomfort related to their condition, such as difficulty breathing, muscle weakness, or organ failure. In contrast, someone who dies suddenly from an accident or trauma may not experience physical pain but may experience shock or disorientation before losing consciousness.
It’s worth noting that many people who have had near-death experiences (NDEs) report feelings of peace, love, and a sense of detachment from their physical body during the experience. However, the nature of NDEs is still poorly understood, and some skeptics argue that these experiences may be the result of physiological or psychological factors rather than evidence of an afterlife.
In conclusion, the concept of the soul and its departure from the body is a matter of belief and spirituality, and there is no scientific evidence to support the idea that the soul leaving the body would cause physical pain. However, the process of dying itself can be accompanied by physical discomfort or pain, depending on the individual’s health status and the underlying cause of death.